Low High-Density Lipoprotein and Risk of Myocardial Infarction

Low HDL is an independent risk factor for myocardial infarction. This paper reviews our current understanding of HDL, HDL structure and function, HDL subclasses, the relationship of low HDL with myocardial infarction, HDL targeted therapy, and clinical trials and studies. Furthermore potential new a...

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Main Authors: A. Ramirez, P. P. Hu
Format: Article
Language:English
Published: SAGE Publishing 2015-01-01
Series:Clinical Medicine Insights: Cardiology
Online Access:https://doi.org/10.4137/CMC.S26624
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spelling doaj-4b3c11b2597e42d3b96196f00f10ebee2020-11-25T03:46:27ZengSAGE PublishingClinical Medicine Insights: Cardiology1179-54682015-01-01910.4137/CMC.S26624Low High-Density Lipoprotein and Risk of Myocardial InfarctionA. Ramirez0P. P. Hu1Riverside Medical Clinic, Riverside, CA, USA.Riverside Medical Clinic, Riverside, CA, USA.Low HDL is an independent risk factor for myocardial infarction. This paper reviews our current understanding of HDL, HDL structure and function, HDL subclasses, the relationship of low HDL with myocardial infarction, HDL targeted therapy, and clinical trials and studies. Furthermore potential new agents, such as alirocumab (praluent) and evolocumab (repatha) are discussed.https://doi.org/10.4137/CMC.S26624
collection DOAJ
language English
format Article
sources DOAJ
author A. Ramirez
P. P. Hu
spellingShingle A. Ramirez
P. P. Hu
Low High-Density Lipoprotein and Risk of Myocardial Infarction
Clinical Medicine Insights: Cardiology
author_facet A. Ramirez
P. P. Hu
author_sort A. Ramirez
title Low High-Density Lipoprotein and Risk of Myocardial Infarction
title_short Low High-Density Lipoprotein and Risk of Myocardial Infarction
title_full Low High-Density Lipoprotein and Risk of Myocardial Infarction
title_fullStr Low High-Density Lipoprotein and Risk of Myocardial Infarction
title_full_unstemmed Low High-Density Lipoprotein and Risk of Myocardial Infarction
title_sort low high-density lipoprotein and risk of myocardial infarction
publisher SAGE Publishing
series Clinical Medicine Insights: Cardiology
issn 1179-5468
publishDate 2015-01-01
description Low HDL is an independent risk factor for myocardial infarction. This paper reviews our current understanding of HDL, HDL structure and function, HDL subclasses, the relationship of low HDL with myocardial infarction, HDL targeted therapy, and clinical trials and studies. Furthermore potential new agents, such as alirocumab (praluent) and evolocumab (repatha) are discussed.
url https://doi.org/10.4137/CMC.S26624
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