More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19

Background. Although severe pneumonia and respiratory compromise have remained the predominant complications of coronavirus disease 19, we are now learning this virus is much more varied in its presentation. In particular, there are increasingly reported cases of thromboembolic events occurring in i...

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Main Authors: Jahinover Mazo, Sukhdev Singh, Zohaib Khan, Allison Foster, Ecaterina Komarnitsky, Abhiram Nagaraj, Soham Patel, Vinaya Kikkeri
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2020/4812036
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spelling doaj-4b336b510a6846968a4938c6a67265f02020-11-25T03:13:21ZengHindawi LimitedCase Reports in Medicine1687-96271687-96352020-01-01202010.1155/2020/48120364812036More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19Jahinover Mazo0Sukhdev Singh1Zohaib Khan2Allison Foster3Ecaterina Komarnitsky4Abhiram Nagaraj5Soham Patel6Vinaya Kikkeri7Department of Radiology, Richmond University Medical Center, New York, NY, USACollege of Medicine, American University of Antigua, New York, NY, USACollege of Medicine, American University of Antigua, New York, NY, USACollege of Medicine, American University of Antigua, New York, NY, USACollege of Medicine, American University of Antigua, New York, NY, USADepartment of Radiology, Richmond University Medical Center, New York, NY, USADepartment of Radiology, Richmond University Medical Center, New York, NY, USADepartment of Radiology, Richmond University Medical Center, New York, NY, USABackground. Although severe pneumonia and respiratory compromise have remained the predominant complications of coronavirus disease 19, we are now learning this virus is much more varied in its presentation. In particular, there are increasingly reported cases of thromboembolic events occurring in infected patients. Case Report. In this report, we present two patients, both under the age of 40 with known risk factors for venous thromboembolism, who presented with respiratory distress. Both patients were diagnosed with SARS-CoV-2 pneumonia and pulmonary embolism requiring management with anticoagulation. Both patients were discharged after a short course in the hospital. Conclusion. The discussion of a hypercoagulable state induced by coronavirus disease 19 has been well documented; however, the exact mechanisms remain unknown. We suspect that a prothrombotic inflammatory response provoked by coronavirus disease could be the culprit, acting as an additive effect on middle-aged patients with known risk factors for venous thromboembolism. We recommend clinicians closely monitor those with known risk factors for pulmonary embolism.http://dx.doi.org/10.1155/2020/4812036
collection DOAJ
language English
format Article
sources DOAJ
author Jahinover Mazo
Sukhdev Singh
Zohaib Khan
Allison Foster
Ecaterina Komarnitsky
Abhiram Nagaraj
Soham Patel
Vinaya Kikkeri
spellingShingle Jahinover Mazo
Sukhdev Singh
Zohaib Khan
Allison Foster
Ecaterina Komarnitsky
Abhiram Nagaraj
Soham Patel
Vinaya Kikkeri
More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19
Case Reports in Medicine
author_facet Jahinover Mazo
Sukhdev Singh
Zohaib Khan
Allison Foster
Ecaterina Komarnitsky
Abhiram Nagaraj
Soham Patel
Vinaya Kikkeri
author_sort Jahinover Mazo
title More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19
title_short More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19
title_full More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19
title_fullStr More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19
title_full_unstemmed More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19
title_sort more than just pneumonia: acute pulmonary embolism in two middle-aged patients with covid-19
publisher Hindawi Limited
series Case Reports in Medicine
issn 1687-9627
1687-9635
publishDate 2020-01-01
description Background. Although severe pneumonia and respiratory compromise have remained the predominant complications of coronavirus disease 19, we are now learning this virus is much more varied in its presentation. In particular, there are increasingly reported cases of thromboembolic events occurring in infected patients. Case Report. In this report, we present two patients, both under the age of 40 with known risk factors for venous thromboembolism, who presented with respiratory distress. Both patients were diagnosed with SARS-CoV-2 pneumonia and pulmonary embolism requiring management with anticoagulation. Both patients were discharged after a short course in the hospital. Conclusion. The discussion of a hypercoagulable state induced by coronavirus disease 19 has been well documented; however, the exact mechanisms remain unknown. We suspect that a prothrombotic inflammatory response provoked by coronavirus disease could be the culprit, acting as an additive effect on middle-aged patients with known risk factors for venous thromboembolism. We recommend clinicians closely monitor those with known risk factors for pulmonary embolism.
url http://dx.doi.org/10.1155/2020/4812036
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