Single-Molecule Real-Time (SMRT) Full-Length RNA-Sequencing Reveals Novel and Distinct mRNA Isoforms in Human Bone Marrow Cell Subpopulations

Single-Molecule Real-Time (SMRT) Full-Length RNA-Sequencing Reveals Novel and Distinct mRNA Isoforms in Human Bone Marrow Cell Subpopulations

Hematopoietic cells are continuously replenished from progenitor cells that reside in the bone marrow. To evaluate molecular changes during this process, we analyzed the transcriptomes of freshly harvested human bone marrow progenitor (lineage-negative) and differentiated (lineage-positive) cells by...

Full description

Bibliographic Details
Main Authors: Anne Deslattes Mays, Marcel Schmidt, Garrett Graham, Elizabeth Tseng, Primo Baybayan, Robert Sebra, Miloslav Sanda, Jean-Baptiste Mazarati, Anna Riegel, Anton Wellstein
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Genes
Subjects:
full length RNAseq
mRNA isoforms
protein isoforms
bone marrow cell subpopulations
Online Access:https://www.mdpi.com/2073-4425/10/4/253

Internet

https://www.mdpi.com/2073-4425/10/4/253

Similar Items