Epidemics on networks with large initial conditions or changing structure.

In this paper we extend previous work deriving dynamic equations governing infectious disease spread on networks. The previous work has implicitly assumed that the disease is initialized by an infinitesimally small proportion of the population. Our modifications allow us to account for an arbitraril...

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Main Author: Joel C Miller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4086930?pdf=render
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spelling doaj-4b0d0bded5a6477e9877097f1f50fa272020-11-24T20:50:06ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0197e10142110.1371/journal.pone.0101421Epidemics on networks with large initial conditions or changing structure.Joel C MillerIn this paper we extend previous work deriving dynamic equations governing infectious disease spread on networks. The previous work has implicitly assumed that the disease is initialized by an infinitesimally small proportion of the population. Our modifications allow us to account for an arbitrarily large initial proportion infected. This helps resolve an apparent paradox in earlier work whereby the number of susceptible individuals could increase if too many individuals were initially infected. It also helps explain an apparent small deviation that has been observed between simulation and theory. An advantage of this modification is that it allows us to account for changes in the structure or behavior of the population during the epidemic.http://europepmc.org/articles/PMC4086930?pdf=render
collection DOAJ
language English
format Article
sources DOAJ
author Joel C Miller
spellingShingle Joel C Miller
Epidemics on networks with large initial conditions or changing structure.
PLoS ONE
author_facet Joel C Miller
author_sort Joel C Miller
title Epidemics on networks with large initial conditions or changing structure.
title_short Epidemics on networks with large initial conditions or changing structure.
title_full Epidemics on networks with large initial conditions or changing structure.
title_fullStr Epidemics on networks with large initial conditions or changing structure.
title_full_unstemmed Epidemics on networks with large initial conditions or changing structure.
title_sort epidemics on networks with large initial conditions or changing structure.
publisher Public Library of Science (PLoS)
series PLoS ONE
issn 1932-6203
publishDate 2014-01-01
description In this paper we extend previous work deriving dynamic equations governing infectious disease spread on networks. The previous work has implicitly assumed that the disease is initialized by an infinitesimally small proportion of the population. Our modifications allow us to account for an arbitrarily large initial proportion infected. This helps resolve an apparent paradox in earlier work whereby the number of susceptible individuals could increase if too many individuals were initially infected. It also helps explain an apparent small deviation that has been observed between simulation and theory. An advantage of this modification is that it allows us to account for changes in the structure or behavior of the population during the epidemic.
url http://europepmc.org/articles/PMC4086930?pdf=render
work_keys_str_mv AT joelcmiller epidemicsonnetworkswithlargeinitialconditionsorchangingstructure
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