Effects of Nandrolone in the Counteraction of Skeletal Muscle Atrophy in a Mouse Model of Muscle Disuse: Molecular Biology and Functional Evaluation.

Muscle disuse produces severe atrophy and a slow-to-fast phenotype transition in the postural Soleus (Sol) muscle of rodents. Antioxidants, amino-acids and growth factors were ineffective to ameliorate muscle atrophy. Here we evaluate the effects of nandrolone (ND), an anabolic steroid, on mouse ske...

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Main Authors: Giulia Maria Camerino, Jean-François Desaphy, Michela De Bellis, Roberta Francesca Capogrosso, Anna Cozzoli, Maria Maddalena Dinardo, Roberta Caloiero, Kejla Musaraj, Adriano Fonzino, Elena Conte, Catherine Jagerschmidt, Florence Namour, Antonella Liantonio, Annamaria De Luca, Diana Conte Camerino, Sabata Pierno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4466268?pdf=render