Stem cell delivery of therapies for brain disorders

Abstract The blood brain barrier (BBB) poses a problem to deliver drugs for brain malignancies and neurodegenerative disorders. Stem cells such as neural stem cells (NSCs) and mesenchymal stem cells (MSCs) can be used to delivery drugs or RNA to the brain. This use of methods to bypass the hurdles o...

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Bibliographic Details
Main Authors: Alexander Aleynik, Kevin M Gernavage, Yasmine SH Mourad, Lauren S Sherman, Katherine Liu, Yuriy A Gubenko, Pranela Rameshwar
Format: Article
Language:English
Published: Wiley 2014-12-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/2001-1326-3-24