From organ to cell: Multi-level telomere length assessment in patients with idiopathic pulmonary fibrosis.
RATIONALE:A subset of patients with idiopathic pulmonary fibrosis (IPF) contains short leukocyte telomeres or telomere related mutations. We previously showed that alveolar type 2 cells have short telomeres in fibrotic lesions. Our objectives were to better understand how telomere shortening associa...
Main Authors: | Aernoud A van Batenburg, Karin M Kazemier, Matthijs F M van Oosterhout, Joanne J van der Vis, Hendrik W van Es, Jan C Grutters, Roel Goldschmeding, Coline H M van Moorsel |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0226785 |
Similar Items
-
The Extent of Inflammatory Cell Infiltrate and Fibrosis in Lungs of Telomere- and Surfactant-Related Familial Pulmonary Fibrosis
by: Aernoud A. van Batenburg, et al.
Published: (2021-09-01) -
Short telomere length in IPF lung associates with fibrotic lesions and predicts survival.
by: Reinier Snetselaar, et al.
Published: (2017-01-01) -
Telomere shortening and DNA damage in culprit cells of different types of progressive fibrosing interstitial lung disease
by: Aernoud A. van Batenburg, et al.
Published: (2021-05-01) -
Understanding Idiopathic Interstitial Pneumonia: A Gene-Based Review of Stressed Lungs
by: Coline H. M. van Moorsel, et al.
Published: (2015-01-01) -
Association between variations in cell cycle genes and idiopathic pulmonary fibrosis.
by: Nicoline M Korthagen, et al.
Published: (2012-01-01)