Staurosporine Induces the Generation of Polyploid Giant Cancer Cells in Non-Small-Cell Lung Carcinoma A549 Cells

Staurosporine Induces the Generation of Polyploid Giant Cancer Cells in Non-Small-Cell Lung Carcinoma A549 Cells

Cultivation of A549 non-small-cell lung carcinoma (NSCLC) cells in the presence of staurosporine (SSP) leads to a reduction or a lack of proliferation in a concentration-dependent manner. This inhibition of proliferation is accompanied by the generation of polyploid giant cancer cells (PGCCs) that a...

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Bibliographic Details
Main Authors:	Alexander Glassmann, Carmen Carrillo Garcia, Viktor Janzen, Dominik Kraus, Nadine Veit, Jochen Winter, Rainer Probstmeier
Format:	Article
Language:	English
Published:	Hindawi Limited 2018-01-01
Series:	Analytical Cellular Pathology
Online Access:	http://dx.doi.org/10.1155/2018/1754085

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