Monoclonal antibodies against peptidorhamnomannans of Scedosporium apiospermum enhance the pathogenicity of the fungus.

Monoclonal antibodies against peptidorhamnomannans of Scedosporium apiospermum enhance the pathogenicity of the fungus.

Scedosporium apiospermum is part of the Pseudallescheria-Scedosporium complex. Peptidorhamnomannans (PRMs) are cell wall glycopeptides present in some fungi, and their structures have been characterized in S. apiospermum, S. prolificans and Sporothrix schenckii. Prior work shows that PRMs can intera...

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Bibliographic Details
Main Authors: Livia C L Lopes, Rodrigo Rollin-Pinheiro, Allan J Guimarães, Vera C B Bittencourt, Luis R Martinez, Wade Koba, Sandra E Farias, Joshua D Nosanchuk, Eliana Barreto-Bergter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2957425?pdf=render

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