Ku protein as a potential human T-cell leukemia virus type 1 (HTLV-1) Tax target in clastogenic chromosomal instability of mammalian cells

Ku protein as a potential human T-cell leukemia virus type 1 (HTLV-1) Tax target in clastogenic chromosomal instability of mammalian cells

<p>Abstract</p> <p>The HTLV-1 Tax oncoprotein rapidly induces cytogenetic damage which can be measured by a significant increase in the number of micronuclei (MN) in cells. Tax is thought to have both aneuploidogenic and clastogenic effects. To examine the cellular target for Tax w...

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Bibliographic Details
Main Authors: Iwanaga Yoichi, Zamboni Daniela, Luisetto Roberto, Majone Franca, Jeang Kuan-Teh
Format: Article
Language:English
Published: BMC 2005-07-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/2/1/45

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