Sequential Experimental Design for Optimal Structural Intervention in Gene Regulatory Networks Based on the Mean Objective Cost of Uncertainty

Scientists are attempting to use models of ever-increasing complexity, especially in medicine, where gene-based diseases such as cancer require better modeling of cell regulation. Complex models suffer from uncertainty and experiments are needed to reduce this uncertainty. Because experiments can be...

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Bibliographic Details
Main Authors: Mahdi Imani, Roozbeh Dehghannasiri, Ulisses M Braga-Neto, Edward R Dougherty
Format: Article
Language:English
Published: SAGE Publishing 2018-08-01
Series:Cancer Informatics
Online Access:https://doi.org/10.1177/1176935118790247