A novel missense mutation in the HSF4 gene of giant pandas with senile congenital cataracts
Abstract Cataracts are a common cause of visual impairment and blindness in mammals. They are usually associated with aging, but approximately one third of cases have a significant genetic component. Cataracts are increasingly prevalent among aging populations of captive giant pandas (Ailuropoda mel...
Main Authors: | Yuyan You, Chao Bai, Xuefeng Liu, Maohua Xia, Yanqiang Yin, Yucun Chen, Wei Wang, Ting Jia, Yan Lu, Tianchun Pu, Chenglin Zhang, Xiaoguang Li, Liqin Wang, Yunfang Xiu, Lili Niu, Jun Zhou, Yang Du, Yanhui Liu, Suhui Xu |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-84741-5 |
Similar Items
-
A novel missense mutation in the gene encoding major intrinsic protein (MIP) in a Giant panda with unilateral cataract formation
by: Chao Bai, et al.
Published: (2021-02-01) -
Genome-wide analysis of methylation in giant pandas with cataract by methylation-dependent restriction-site associated DNA sequencing (MethylRAD).
by: Yuyan You, et al.
Published: (2019-01-01) -
Structural analysis of missense mutations occurring in the DNA-binding domain of HSF4 associated with congenital cataracts
by: Zaiyu Xiao, et al.
Published: (2020-01-01) -
Sequelae of neglected senile cataract
by: Azhany Y, et al.
Published: (2013-05-01) -
Topical glutathione therapy in senile cataracts Cataract III
by: Sharma Y, et al.
Published: (1989-01-01)