High-throughput screening for novel inhibitors of Neisseria gonorrhoeae penicillin-binding protein 2.

The increasing prevalence of N. gonorrhoeae strains exhibiting decreased susceptibility to third-generation cephalosporins and the recent isolation of two distinct strains with high-level resistance to cefixime or ceftriaxone heralds the possible demise of β-lactam antibiotics as effective treatment...

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Bibliographic Details
Main Authors: Alena Fedarovich, Kevin A Djordjevic, Shauna M Swanson, Yuri K Peterson, Robert A Nicholas, Christopher Davies
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3458020?pdf=render

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