Squalene-Based Influenza Vaccine Adjuvants and Their Impact on the Hemagglutinin-Specific B Cell Response

Squalene-Based Influenza Vaccine Adjuvants and Their Impact on the Hemagglutinin-Specific B Cell Response

Influenza infections continue to cause significant annual morbidity and mortality despite ongoing influenza vaccine research. Adjuvants are administered in conjunction with influenza vaccines to enhance the immune response and strengthen protection against disease. Squalene-based emulsion adjuvants...

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Bibliographic Details
Main Authors: Phuong Nguyen-Contant, Mark Y. Sangster, David J. Topham
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Pathogens
Subjects:
squalene-based adjuvant
influenza A virus
memory B cells
hemagglutinin
antibody
germinal center
Online Access:https://www.mdpi.com/2076-0817/10/3/355

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