CCR5 is a novel target for the treatment of experimental alopecia areata
Abstract Background Alopecia areata (AA) is an organ‐specific and cell‐mediated autoimmune disease. Hair follicle autoantigens are disclosed to these autoreactive NKG2D+CD8+ T cells. A Th1 chemokine, CXCL10, is highly expressed on hair follicle keratinocytes and leads to the infiltration of CXCR3+ a...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-04-01
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Series: | Journal of Cutaneous Immunology and Allergy |
Subjects: | |
Online Access: | https://doi.org/10.1002/cia2.12092 |