Culture and genome-based analysis of four soil Clostridium isolates reveal their potential for antimicrobial production

Culture and genome-based analysis of four soil Clostridium isolates reveal their potential for antimicrobial production

Abstract Background Soil bacteria are a major source of specialized metabolites including antimicrobial compounds. Yet, one of the most diverse genera of bacteria ubiquitously present in soil, Clostridium, has been largely overlooked in bioactive compound discovery. As Clostridium spp. thrive in ext...

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Bibliographic Details
Main Authors: Amila S. N. W. Pahalagedara, Ruy Jauregui, Paul Maclean, Eric Altermann, Steve Flint, Jon Palmer, Gale Brightwell, Tanushree Barua Gupta
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Genomics
Subjects:
Clostridium spp.
Antimicrobial
Biosynthesis gene clusters
Genome mining
Ribosomally synthesized post-translationally modified peptides
Non-ribosomal peptides
Online Access:https://doi.org/10.1186/s12864-021-08005-2

Internet

https://doi.org/10.1186/s12864-021-08005-2

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