Comprehensive Analysis of HERV Transcriptome in HIV+ Cells: Absence of HML2 Activation and General Downregulation of Individual HERV Loci

Comprehensive Analysis of HERV Transcriptome in HIV+ Cells: Absence of HML2 Activation and General Downregulation of Individual HERV Loci

Human endogenous retrovirus (HERV) expression is currently studied for its possible activation by HIV infection. In this context, the HERV-K(HML2) group is the most investigated: it has been proposed that HIV-1 infection can prompt HML2 transcription, and that HML2 proteins can affect HIV-1 replicat...

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Bibliographic Details
Main Authors: Nicole Grandi, Maria Paola Pisano, Sante Scognamiglio, Eleonora Pessiu, Enzo Tramontano
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Viruses
Subjects:
HERV
HIV
endogenous retroviruses
RNAseq
HERV expression
HML2
Online Access:https://www.mdpi.com/1999-4915/12/4/481

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