Functional comparison between genes dysregulated in ulcerative colitis and colorectal carcinoma.

BACKGROUND: Patients with ulcerative colitis (UC) are predisposed to colitis-associated colorectal cancer (CAC). However, the transcriptional mechanism of the transformation from UC to CAC is not fully understood. METHODOLOGY: Firstly, we showed that CAC and non-UC-associated CRC were very similar i...

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Bibliographic Details
Main Authors: Wenyuan Zhao, Lishuang Qi, Yao Qin, Hongwei Wang, Beibei Chen, Ruiping Wang, Yunyan Gu, Chunyang Liu, Chenguang Wang, Zheng Guo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3750042?pdf=render