Nuclear shuttling of Y Box binding protein-1, its clinical relevance in cancer and as a therapeutic target

Nuclear shuttling of Y Box binding protein-1, its clinical relevance in cancer and as a therapeutic target

Y-box binding protein 1 (YB-1) is an imperative biomarker for the clinical out-come of cancer patients. An overexpression of YB-1 in cancerous and adjoining tissues is an indication of aggressiveness and advanced stages. In normal resting cells, YB-1 is localized in cytoplasm while in stress conditi...

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Bibliographic Details
Main Authors: Vinoth Prasanna Gunasekaran, Kumari Nishi, Vilwanathan Ravikumar, Ganeshan Mathan
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2016-04-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Cancer
Nuclear shuttling
Y-box binding protein 1
Online Access:https://www.banglajol.info/index.php/BJP/article/view/26759

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