A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade

A diastereoselective approach to axially chiral imidazopyridine-containing biaryls has been developed. The reactions proceed through a radical cyclization cascade to construct the biaryls with good to excellent central-to-axial chirality transfer.

Bibliographic Details
Main Authors: Hong Yan, Zhong-Yi Mao, Zhong-Wei Hou, Jinshuai Song, Hai-Chao Xu
Format: Article
Language:English
Published: Beilstein-Institut 2019-03-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.15.76

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