A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade

A diastereoselective approach to axially chiral imidazopyridine-containing biaryls has been developed. The reactions proceed through a radical cyclization cascade to construct the biaryls with good to excellent central-to-axial chirality transfer.

Bibliographic Details
Main Authors:	Hong Yan, Zhong-Yi Mao, Zhong-Wei Hou, Jinshuai Song, Hai-Chao Xu
Format:	Article
Language:	English
Published:	Beilstein-Institut 2019-03-01
Series:	Beilstein Journal of Organic Chemistry
Subjects:	axial chirality biaryl electrochemistry oxidation radical
Online Access:	https://doi.org/10.3762/bjoc.15.76

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spelling	doaj-4a82068ceba84f54873d907e9b5b7ab62021-03-02T09:54:39ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972019-03-0115179580010.3762/bjoc.15.761860-5397-15-76A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascadeHong Yan0Zhong-Yi Mao1Zhong-Wei Hou2Jinshuai Song3Hai-Chao Xu4State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province, iChEM and College of Chemistry and Chemical Engineering, Xiamen University, People’s Republic of ChinaState Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province, iChEM and College of Chemistry and Chemical Engineering, Xiamen University, People’s Republic of ChinaState Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province, iChEM and College of Chemistry and Chemical Engineering, Xiamen University, People’s Republic of ChinaCollege of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, People’s Republic of ChinaState Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province, iChEM and College of Chemistry and Chemical Engineering, Xiamen University, People’s Republic of ChinaA diastereoselective approach to axially chiral imidazopyridine-containing biaryls has been developed. The reactions proceed through a radical cyclization cascade to construct the biaryls with good to excellent central-to-axial chirality transfer.https://doi.org/10.3762/bjoc.15.76axial chiralitybiarylelectrochemistryoxidationradical
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Hong Yan Zhong-Yi Mao Zhong-Wei Hou Jinshuai Song Hai-Chao Xu
spellingShingle	Hong Yan Zhong-Yi Mao Zhong-Wei Hou Jinshuai Song Hai-Chao Xu A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade Beilstein Journal of Organic Chemistry axial chirality biaryl electrochemistry oxidation radical
author_facet	Hong Yan Zhong-Yi Mao Zhong-Wei Hou Jinshuai Song Hai-Chao Xu
author_sort	Hong Yan
title	A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade
title_short	A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade
title_full	A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade
title_fullStr	A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade
title_full_unstemmed	A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade
title_sort	diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade
publisher	Beilstein-Institut
series	Beilstein Journal of Organic Chemistry
issn	1860-5397
publishDate	2019-03-01
description	A diastereoselective approach to axially chiral imidazopyridine-containing biaryls has been developed. The reactions proceed through a radical cyclization cascade to construct the biaryls with good to excellent central-to-axial chirality transfer.
topic	axial chirality biaryl electrochemistry oxidation radical
url	https://doi.org/10.3762/bjoc.15.76
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A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade

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