Periodontal Inflammation-Triggered by Periodontal Ligament Stem Cell Pyroptosis Exacerbates Periodontitis

Periodontal Inflammation-Triggered by Periodontal Ligament Stem Cell Pyroptosis Exacerbates Periodontitis

Periodontitis is an immune inflammatory disease that leads to progressive destruction of bone and connective tissue, accompanied by the dysfunction and even loss of periodontal ligament stem cells (PDLSCs). Pyroptosis mediated by gasdermin-D (GSDMD) participates in the pathogenesis of inflammatory d...

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Bibliographic Details
Main Authors: Qin Chen, Xingguang Liu, Dingyu Wang, Jisi Zheng, Lu Chen, Qianyang Xie, Xiaohan Liu, Sujuan Niu, Guanlin Qu, Jianfeng Lan, Jing Li, Chi Yang, Duohong Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
GSDMD
IL-1β
PDLSC
periodontitis
pyroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.663037/full

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