Expression of SAA1, SAA2 and SAA4 genes in human primary monocytes and monocyte-derived macrophages.

Circulating serum amyloid A (SAA) is increased in various inflammatory conditions. The human SAA protein family comprises the acute phase SAA1/SAA2, known to activate a large set of innate and adaptive immune cells, and the constitutive SAA4. The liver synthesis of SAA1/SAA2 is well-established but...

Full description

Bibliographic Details
Main Authors: Claire Jumeau, Fawaz Awad, Eman Assrawi, Laetitia Cobret, Philippe Duquesnoy, Irina Giurgea, Dominique Valeyre, Gilles Grateau, Serge Amselem, Jean-François Bernaudin, Sonia-Athina Karabina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217005