Screening and Identification of Key Genes for Activation of Islet Stellate Cell

Screening and Identification of Key Genes for Activation of Islet Stellate Cell

BackgroundIt has been demonstrated that activated islet stellate cells (ISCs) play a critical role in islet fibrogenesis and significantly contribute to the progression of type 2 diabetes mellitus. However, the key molecules responsible for ISCs activation have not yet been determined. This study ai...

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Bibliographic Details
Main Authors: Xiaohang Wang, Vladmir Carvalho, Qianqian Wang, Jinbang Wang, Tingting Li, Yang Chen, Chengming Ni, Lili Liu, Yang Yuan, Shanhu Qiu, Zilin Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Endocrinology
Subjects:
islet stellate cell
RNA-seq
Fos
Pdpn
Bad
islet fibrosis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.695467/full

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