A Novel, Noncanonical BMP Pathway Modulates Synapse Maturation at the Drosophila Neuromuscular Junction.

A Novel, Noncanonical BMP Pathway Modulates Synapse Maturation at the Drosophila Neuromuscular Junction.

At the Drosophila NMJ, BMP signaling is critical for synapse growth and homeostasis. Signaling by the BMP7 homolog, Gbb, in motor neurons triggers a canonical pathway-which modulates transcription of BMP target genes, and a noncanonical pathway-which connects local BMP/BMP receptor complexes with th...

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Bibliographic Details
Main Authors: Mikolaj J Sulkowski, Tae Hee Han, Carolyn Ott, Qi Wang, Esther M Verheyen, Jennifer Lippincott-Schwartz, Mihaela Serpe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4729469?pdf=render

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