Modelling TERT regulation across 19 different cancer types based on the MIPRIP 2.0 gene regulatory network approach
Abstract Background Reactivation of the telomerase reverse transcriptase gene TERT is a central feature for unlimited proliferation of the majority of cancers. However, the underlying regulatory processes are only partly understood. Results We assembled regulator binding information from serveral so...
Main Authors: | Alexandra M. Poos, Theresa Kordaß, Amol Kolte, Volker Ast, Marcus Oswald, Karsten Rippe, Rainer König |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-12-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-019-3323-2 |
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