Endoplasmic Reticulum Stress, a Target for Drug Design and Drug Resistance in Parasitosis

Endoplasmic Reticulum Stress, a Target for Drug Design and Drug Resistance in Parasitosis

Endoplasmic reticulum stress (ER stress) can be induced when cellular protein homeostasis is damaged, and cells can activate the unfolded protein response (UPR) to restore protein homeostasis or induce cell death to facilitate the survival of the whole system. Globally, parasites are a constant thre...

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Bibliographic Details
Main Authors: Mei Peng, Fang Chen, Zhongdao Wu, Jia Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Microbiology
Subjects:
endoplasmic reticulum stress
drug targets
parasite
parasitosis
drug resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.670874/full

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