Cryptotanshinone attenuates the stemness of non-small cell lung cancer cells via promoting TAZ translocation from nuclear to cytoplasm

Cryptotanshinone attenuates the stemness of non-small cell lung cancer cells via promoting TAZ translocation from nuclear to cytoplasm

Abstract Background Cancer stem cells (CSCs) are regarded as the root of tumor progression, thus representing an anti-cancer therapy through targeting this cell sub-population. Methods Non-small cell lung cancer (NSCLC) CSCs were enriched by non-adherent spheroid formation analysis. Lentivirus infec...

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Bibliographic Details
Main Authors: Linling Jin, Zhenzhen Wu, Yanli Wang, Xin Zhao
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Chinese Medicine
Subjects:
Cryptotanshinone
Stemness
Non-small cell lung cancer
TAZ
Hippo
Online Access:http://link.springer.com/article/10.1186/s13020-020-00348-4

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