Structural snapshot of a bacterial phytochrome in its functional intermediate state

Phytochromes are photoreceptors that are present in plants, bacteria and fungi. Here the authors present crystal structures of the phytochrome Agp2 from Agrobacterium fabrum in the parent Pfr state as well as a functional Meta-F intermediate and discuss mechanistic implications for photoconversion.

Bibliographic Details
Main Authors:	Andrea Schmidt, Luisa Sauthof, Michal Szczepek, Maria Fernandez Lopez, Francisco Velazquez Escobar, Bilal M. Qureshi, Norbert Michael, David Buhrke, Tammo Stevens, Dennis Kwiatkowski, David von Stetten, Maria Andrea Mroginski, Norbert Krauß, Tilman Lamparter, Peter Hildebrandt, Patrick Scheerer
Format:	Article
Language:	English
Published:	Nature Publishing Group 2018-11-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-018-07392-7

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spelling	doaj-4a48f3e973d74e48ad18d6b2ef85136d2021-05-11T09:35:28ZengNature Publishing GroupNature Communications2041-17232018-11-019111310.1038/s41467-018-07392-7Structural snapshot of a bacterial phytochrome in its functional intermediate stateAndrea Schmidt0Luisa Sauthof1Michal Szczepek2Maria Fernandez Lopez3Francisco Velazquez Escobar4Bilal M. Qureshi5Norbert Michael6David Buhrke7Tammo Stevens8Dennis Kwiatkowski9David von Stetten10Maria Andrea Mroginski11Norbert Krauß12Tilman Lamparter13Peter Hildebrandt14Patrick Scheerer15Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal TransductionCharité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal TransductionCharité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal TransductionTechnische Universität Berlin, Institut für ChemieTechnische Universität Berlin, Institut für ChemieCharité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal TransductionTechnische Universität Berlin, Institut für ChemieTechnische Universität Berlin, Institut für ChemieCharité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal TransductionCharité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal TransductionStructural Biology Group, European Synchrotron Radiation FacilityTechnische Universität Berlin, Institut für ChemieKarlsruhe Institute of Technology (KIT), Botanical InstituteKarlsruhe Institute of Technology (KIT), Botanical InstituteTechnische Universität Berlin, Institut für ChemieCharité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Physics and Biophysics, Group Protein X-ray Crystallography and Signal TransductionPhytochromes are photoreceptors that are present in plants, bacteria and fungi. Here the authors present crystal structures of the phytochrome Agp2 from Agrobacterium fabrum in the parent Pfr state as well as a functional Meta-F intermediate and discuss mechanistic implications for photoconversion.https://doi.org/10.1038/s41467-018-07392-7
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Andrea Schmidt Luisa Sauthof Michal Szczepek Maria Fernandez Lopez Francisco Velazquez Escobar Bilal M. Qureshi Norbert Michael David Buhrke Tammo Stevens Dennis Kwiatkowski David von Stetten Maria Andrea Mroginski Norbert Krauß Tilman Lamparter Peter Hildebrandt Patrick Scheerer
spellingShingle	Andrea Schmidt Luisa Sauthof Michal Szczepek Maria Fernandez Lopez Francisco Velazquez Escobar Bilal M. Qureshi Norbert Michael David Buhrke Tammo Stevens Dennis Kwiatkowski David von Stetten Maria Andrea Mroginski Norbert Krauß Tilman Lamparter Peter Hildebrandt Patrick Scheerer Structural snapshot of a bacterial phytochrome in its functional intermediate state Nature Communications
author_facet	Andrea Schmidt Luisa Sauthof Michal Szczepek Maria Fernandez Lopez Francisco Velazquez Escobar Bilal M. Qureshi Norbert Michael David Buhrke Tammo Stevens Dennis Kwiatkowski David von Stetten Maria Andrea Mroginski Norbert Krauß Tilman Lamparter Peter Hildebrandt Patrick Scheerer
author_sort	Andrea Schmidt
title	Structural snapshot of a bacterial phytochrome in its functional intermediate state
title_short	Structural snapshot of a bacterial phytochrome in its functional intermediate state
title_full	Structural snapshot of a bacterial phytochrome in its functional intermediate state
title_fullStr	Structural snapshot of a bacterial phytochrome in its functional intermediate state
title_full_unstemmed	Structural snapshot of a bacterial phytochrome in its functional intermediate state
title_sort	structural snapshot of a bacterial phytochrome in its functional intermediate state
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2018-11-01
description	Phytochromes are photoreceptors that are present in plants, bacteria and fungi. Here the authors present crystal structures of the phytochrome Agp2 from Agrobacterium fabrum in the parent Pfr state as well as a functional Meta-F intermediate and discuss mechanistic implications for photoconversion.
url	https://doi.org/10.1038/s41467-018-07392-7
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Structural snapshot of a bacterial phytochrome in its functional intermediate state

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