Long non-coding RNA GAS5 controls human embryonic stem cell self-renewal by maintaining NODAL signalling
Long non-coding RNAs (lncRNA) are known to regulate human embryonic stem cell (hESC) self-renewal. Here, the authors identify lncRNA growth-arrest-specific transcript 5 (GAS5) that regulates pluripotency via modulation of NODAL signalling to maintain self-renewal in hESCs.
Bibliographic Details
| Main Authors: |
Chen Xu,
Yan Zhang,
Qiaoling Wang,
Zhenyu Xu,
Junfeng Jiang,
Yuping Gao,
Minzhi Gao,
Jiuhong Kang,
Minjuan Wu,
Jun Xiong,
Kaihong Ji,
Wen Yuan,
Yue Wang,
Houqi Liu |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2016-11-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/ncomms13287
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