Immunological Demyelination Triggers Macrophage/Microglial Cells Activation without Inducing Astrogliosis
The glial scar formed by reactive astrocytes and axon growth inhibitors associated with myelin play important roles in the failure of axonal regeneration following central nervous system (CNS) injury. Our laboratory has previously demonstrated that immunological demyelination of the CNS facilitates...
Main Authors: | Frank Cloutier, Ilse Sears-Kraxberger, Krista Keachie, Hans S. Keirstead |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2013-01-01
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Series: | Clinical and Developmental Immunology |
Online Access: | http://dx.doi.org/10.1155/2013/812456 |
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