Cytotoxic cationic peptides as а ligands for receptor nucleolin

Background. Chaperone proteins nucleolin (NCL, or C23) and nucleophosmin (NPM, or B23) regulate key cell functions. The most tumors are characterized by over-expression of these proteins, especially in cell nuclei and on the сell surface, as NCL. Differential expression of NCL/NPM in tumor and norma...

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Bibliographic Details
Main Authors: A. A. Lushnikova, A. V. Kostarev, D. A. Ponkratova, A. V. Onyan, E. G. Glubokova, S. M. Andreev
Format: Article
Language:Russian
Published: ABV-press 2018-11-01
Series:Uspehi Molekulârnoj Onkologii
Subjects:
Online Access:https://umo.abvpress.ru/jour/article/view/166