Bilateral Pulmonary Embolism in a 12-Year-Old Girl with Steroid-Resistant Nephrotic Syndrome

Nephrotic syndrome is the most common glomerular disease among children. Although most cases respond to steroid therapy, approximately 10–20% of patients exhibit resistance to conventional steroid therapy and are labeled as steroid-resistant. Such patients are at risk of complications, including inf...

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Main Authors: Osama Y. Safdar, Rahaf H. Rajab, Rand G. Alghanemi, Gazal A. Tantawi, Noora A. Alsulami, Aeshah A. Alsayed, Abdullah K. Habiballah
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Children
Subjects:
Online Access:https://www.mdpi.com/2227-9067/7/6/62
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spelling doaj-4a3f4f6155474a73a7a4fe4dcc3a3f472021-04-02T15:38:00ZengMDPI AGChildren2227-90672020-06-017626210.3390/children7060062Bilateral Pulmonary Embolism in a 12-Year-Old Girl with Steroid-Resistant Nephrotic SyndromeOsama Y. Safdar0Rahaf H. Rajab1Rand G. Alghanemi2Gazal A. Tantawi3Noora A. Alsulami4Aeshah A. Alsayed5Abdullah K. Habiballah6Pediatric Nephrology Center of Excellence, Pediatric Department, Faculty of Medicine, King Abdulaziz University, Jeddah 21414, Saudi ArabiaFaculty of Medicine, King Abdulaziz University, Jeddah 21414, Saudi ArabiaFaculty of Medicine, King Abdulaziz University, Jeddah 21414, Saudi ArabiaFaculty of Medicine, King Abdulaziz University, Jeddah 21414, Saudi ArabiaFaculty of Medicine, King Abdulaziz University, Jeddah 21414, Saudi ArabiaFaculty of Medicine, King Abdulaziz University, Jeddah 21414, Saudi ArabiaFaculty of Medicine, King Abdulaziz University, Jeddah 21414, Saudi ArabiaNephrotic syndrome is the most common glomerular disease among children. Although most cases respond to steroid therapy, approximately 10–20% of patients exhibit resistance to conventional steroid therapy and are labeled as steroid-resistant. Such patients are at risk of complications, including infection, thrombosis, and chronic kidney disease. Nephrotic syndrome is considered a thrombogenic condition. Pulmonary embolism is associated with high mortality, and early treatment is essential for the survival of patients. Here, we report the case of a 12-year-old girl with late steroid resistance who developed bilateral pulmonary embolism.https://www.mdpi.com/2227-9067/7/6/62nephrotic syndromepulmonary embolismsteroid resistance
collection DOAJ
language English
format Article
sources DOAJ
author Osama Y. Safdar
Rahaf H. Rajab
Rand G. Alghanemi
Gazal A. Tantawi
Noora A. Alsulami
Aeshah A. Alsayed
Abdullah K. Habiballah
spellingShingle Osama Y. Safdar
Rahaf H. Rajab
Rand G. Alghanemi
Gazal A. Tantawi
Noora A. Alsulami
Aeshah A. Alsayed
Abdullah K. Habiballah
Bilateral Pulmonary Embolism in a 12-Year-Old Girl with Steroid-Resistant Nephrotic Syndrome
Children
nephrotic syndrome
pulmonary embolism
steroid resistance
author_facet Osama Y. Safdar
Rahaf H. Rajab
Rand G. Alghanemi
Gazal A. Tantawi
Noora A. Alsulami
Aeshah A. Alsayed
Abdullah K. Habiballah
author_sort Osama Y. Safdar
title Bilateral Pulmonary Embolism in a 12-Year-Old Girl with Steroid-Resistant Nephrotic Syndrome
title_short Bilateral Pulmonary Embolism in a 12-Year-Old Girl with Steroid-Resistant Nephrotic Syndrome
title_full Bilateral Pulmonary Embolism in a 12-Year-Old Girl with Steroid-Resistant Nephrotic Syndrome
title_fullStr Bilateral Pulmonary Embolism in a 12-Year-Old Girl with Steroid-Resistant Nephrotic Syndrome
title_full_unstemmed Bilateral Pulmonary Embolism in a 12-Year-Old Girl with Steroid-Resistant Nephrotic Syndrome
title_sort bilateral pulmonary embolism in a 12-year-old girl with steroid-resistant nephrotic syndrome
publisher MDPI AG
series Children
issn 2227-9067
publishDate 2020-06-01
description Nephrotic syndrome is the most common glomerular disease among children. Although most cases respond to steroid therapy, approximately 10–20% of patients exhibit resistance to conventional steroid therapy and are labeled as steroid-resistant. Such patients are at risk of complications, including infection, thrombosis, and chronic kidney disease. Nephrotic syndrome is considered a thrombogenic condition. Pulmonary embolism is associated with high mortality, and early treatment is essential for the survival of patients. Here, we report the case of a 12-year-old girl with late steroid resistance who developed bilateral pulmonary embolism.
topic nephrotic syndrome
pulmonary embolism
steroid resistance
url https://www.mdpi.com/2227-9067/7/6/62
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