High Expression of PHGDH Predicts Poor Prognosis in Non–Small Cell Lung Cancer

High Expression of PHGDH Predicts Poor Prognosis in Non–Small Cell Lung Cancer

Tumors have exceptionally high demands for energy and anabolism because of their rapid growth. The de novo serine synthesis pathway initiated by phosphoglycerate dehydrogenase (PHGDH) has been recognized as a hallmark of metabolic adaption in carcinogenesis. The oncogenic role and prognostic value o...

Full description

Bibliographic Details
Main Authors: Jinhong Zhu, Jianqun Ma, Xudong Wang, Tianjiao Ma, Shu Zhang, Wei Wang, Xiaoyu Zhou, Jiahai Shi
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523316301140

Similar Items

Similar Items