The frequency of blood-born viral infections in a population of multitransfused Brazilian patients Freqüência de infecções virais transmitidas por transfusões em uma população de pacientes brasileiros multitransfundidos

The frequency of viral markers for hepatitis B (HBV) and C (HCV), human immunodeficiency virus-1 (HIV-1) and human T-lymphotropic virus-1 (HTLV-1) was evaluated in 32 Brazilian ß-thalassemia multitransfused patients. Additionaly the serum concentrations of ferritin and alanine aspartate transaminase...

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Bibliographic Details
Main Authors: Dimas T. Covas, Edmir Boturão Neto, Marco A. Zago
Format: Article
Language:English
Published: Universidade de São Paulo 1993-06-01
Series:Revista do Instituto de Medicina Tropical de São Paulo
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651993000300008
Description
Summary:The frequency of viral markers for hepatitis B (HBV) and C (HCV), human immunodeficiency virus-1 (HIV-1) and human T-lymphotropic virus-1 (HTLV-1) was evaluated in 32 Brazilian ß-thalassemia multitransfused patients. Additionaly the serum concentrations of ferritin and alanine aspartate transaminase (ALAT) were determined. The results show a high prevalence of markers of infection by HBV (25.0%) and HCV (46.8%) and a low prevalence of markers for HIV-1 and HTLV-1. No correlations were demonstrated between the presence of the hepatitis markers and the number of units transfused or the serum concentrations of ferritin and ALAT.<br>A freqüência de marcadores virais para hepatite B (HBV), C (HCV), vírus da imunodeficiência humana-1 (HIV-1) e vírus linfotrópico-T humano (HTLV-1) foi avaliada em 32 pacientes brasileiros multitransfundidos, portadores de ß-talassemia. Adicionalmente determinou-se a concentração sérica de transaminase alani-na aspártica (ALAT) e de ferritina. Os resultados mostraram alta prevalência de marcadores para HBV (25,0%) e HCV (46,8%) e baixa prevalência de marcadores para HIV-1 e HTLV-1. Não se demonstrou correlação entre a presença de marcadores para hepatite e o número de unidades transfundidas ou com as concentrações séricas de ferritina e ALAT.
ISSN:0036-4665
1678-9946