Specific capture and whole-genome sequencing of viruses from clinical samples.

Specific capture and whole-genome sequencing of viruses from clinical samples.

Whole genome sequencing of viruses directly from clinical samples is integral for understanding the genetics of host-virus interactions. Here, we report the use of sample sparing target enrichment (by hybridisation) for viral nucleic acid separation and deep-sequencing of herpesvirus genomes directl...

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Bibliographic Details
Main Authors: Daniel P Depledge, Anne L Palser, Simon J Watson, Imogen Yi-Chun Lai, Eleanor R Gray, Paul Grant, Ravinder K Kanda, Emily Leproust, Paul Kellam, Judith Breuer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3220689?pdf=render

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