A cancer derived mutation in the Retinoblastoma gene with a distinct defect for LXCXE dependent interactions

A cancer derived mutation in the Retinoblastoma gene with a distinct defect for LXCXE dependent interactions

<p>Abstract</p> <p>Background</p> <p>The interaction between viral oncoproteins such as Simian virus 40 TAg, adenovirus E1A, and human papilloma virus E7, and the retinoblastoma protein (pRB) occurs through a well characterized peptide sequence, LXCXE, on the viral prot...

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Bibliographic Details
Main Authors: Demone Jordan, Francis Sarah M, Henley Shauna A, Ainsworth Peter, Dick Frederick A
Format: Article
Language:English
Published: BMC 2010-03-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/10/1/8

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