p62 Overexpression Promotes Bone Metastasis of Lung Adenocarcinoma out of LC3-Dependent Autophagy

p62 Overexpression Promotes Bone Metastasis of Lung Adenocarcinoma out of LC3-Dependent Autophagy

p62 protein has been implicated in bone metastasis and is a multifunctional adaptor protein usually correlated with autophagy. Herein, we investigated p62 expression and its prognostic significance in bone metastasis of lung adenocarcinoma, and analyzed whether the mechanism involved depends on auto...

Full description

Bibliographic Details
Main Authors: Dongqi Li, Chuanchun He, Fan Ye, En Ye, Hao He, Gong Chen, Jing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
p62/sequestosome 1
bone metastasis
lung cancer
prognosis
autophagy
LC3
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.609548/full

Similar Items

Similar Items