Autophagy differentially regulates TNF receptor Fn14 by distinct mammalian Atg8 proteins

Autophagy differentially regulates TNF receptor Fn14 by distinct mammalian Atg8 proteins

The TNF receptor Fn14 is a short-lived protein. Here the authors show that Fn14 turnover is regulated by selective autophagy, with different ATG8 proteins having distinct roles during the process.

Bibliographic Details
Main Authors: Hila Winer, Milana Fraiberg, Adi Abada, Tali Dadosh, Bat-Chen Tamim-Yecheskel, Zvulun Elazar
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06275-1
Description
Summary:The TNF receptor Fn14 is a short-lived protein. Here the authors show that Fn14 turnover is regulated by selective autophagy, with different ATG8 proteins having distinct roles during the process.
ISSN:2041-1723

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