Discriminating survival outcomes in patients with glioblastoma using a simulation-based, patient-specific response metric.

Discriminating survival outcomes in patients with glioblastoma using a simulation-based, patient-specific response metric.

Accurate clinical assessment of a patient's response to treatment for glioblastoma multiforme (GBM), the most malignant type of primary brain tumor, is undermined by the wide patient-to-patient variability in GBM dynamics and responsiveness to therapy. Using computational models that account fo...

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Bibliographic Details
Main Authors: Maxwell Lewis Neal, Andrew D Trister, Tyler Cloke, Rita Sodt, Sunyoung Ahn, Anne L Baldock, Carly A Bridge, Albert Lai, Timothy F Cloughesy, Maciej M Mrugala, Jason K Rockhill, Russell C Rockne, Kristin R Swanson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3553125?pdf=render

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http://europepmc.org/articles/PMC3553125?pdf=render

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