TLR and NKG2D signaling pathways mediate CS-induced pulmonary pathologies.

Long-term exposure to cigarette smoke (CS) can have deleterious effects on lung epithelial cells including cell death and the initiation of inflammatory responses. CS-induced cell injury can elaborate cell surface signals and cellular byproducts that stimulate immune system surveillance. Our previou...

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Bibliographic Details
Main Authors: Brian W Wortham, Bryan L Eppert, Jennifer L Flury, Sara Morgado Garcia, Michael T Borchers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3793989?pdf=render