Activation of mGlu3 receptors stimulates the production of GDNF in striatal neurons.

Activation of mGlu3 receptors stimulates the production of GDNF in striatal neurons.

Metabotropic glutamate (mGlu) receptors have been considered potential targets for the therapy of experimental parkinsonism. One hypothetical advantage associated with the use of mGlu receptor ligands is the lack of the adverse effects typically induced by ionotropic glutamate receptor antagonists,...

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Main Authors: Giuseppe Battaglia, Gemma Molinaro, Barbara Riozzi, Marianna Storto, Carla L Busceti, Paola Spinsanti, Domenico Bucci, Valentina Di Liberto, Giuseppina Mudò, Corrado Corti, Mauro Corsi, Ferdinando Nicoletti, Natale Belluardo, Valeria Bruno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2719807?pdf=render

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