Characterization of PTPRG in knockdown and phosphatase-inactive mutant mice and substrate trapping analysis of PTPRG in mammalian cells.

Characterization of PTPRG in knockdown and phosphatase-inactive mutant mice and substrate trapping analysis of PTPRG in mammalian cells.

Receptor tyrosine phosphatase gamma (PTPRG, or RPTPγ) is a mammalian receptor-like tyrosine phosphatase which is highly expressed in the nervous system as well as other tissues. Its function and biochemical characteristics remain largely unknown. We created a knockdown (KD) line of this gene in mous...

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Bibliographic Details
Main Authors: Wandong Zhang, Katerina V Savelieva, David T Tran, Vladimir M Pogorelov, Emily B Cullinan, Kevin B Baker, Kenneth A Platt, Sean Hu, Indrani Rajan, Nianhua Xu, Thomas H Lanthorn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3447766?pdf=render

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