Dimethyl Fumarate Alleviates Dextran Sulfate Sodium-Induced Colitis, through the Activation of Nrf2-Mediated Antioxidant and Anti-Inflammatory Pathways

Dimethyl Fumarate Alleviates Dextran Sulfate Sodium-Induced Colitis, through the Activation of Nrf2-Mediated Antioxidant and Anti-Inflammatory Pathways

Oxidative stress and chronic inflammation play critical roles in the pathogenesis of ulcerative colitis (UC) and inflammatory bowel diseases (IBD). A previous study has demonstrated that dimethyl fumarate (DMF) protects mice from dextran sulfate sodium (DSS)-induced colitis via its potential antioxi...

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Bibliographic Details
Main Authors: Shiri Li, Chie Takasu, Hien Lau, Lourdes Robles, Kelly Vo, Ted Farzaneh, Nosratola D. Vaziri, Michael J. Stamos, Hirohito Ichii
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Antioxidants
Subjects:
colitis
Nrf2
dimethyl fumarate
antioxidant
anti-inflammation
Online Access:https://www.mdpi.com/2076-3921/9/4/354

Internet

https://www.mdpi.com/2076-3921/9/4/354

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