Selective retina therapy for subretinal fluid associated with choroidal nevus

• Main Authors: Manabu Yamamoto, Yoko Miura, Akika Kyo, Kumiko Hirayama, Takeya Kohno, Dirk Theisen-Kunde, Ralf Brinkmann, Shigeru Honda
• Format: Article
• Language: English
• Published: Elsevier 2020-09-01
• Series: American Journal of Ophthalmology Case Reports
• Subjects: Laser therapy; Choroidal tumor; Retinal pigment epithelium; Retinal disorder
• Online Access: http://www.sciencedirect.com/science/article/pii/S2451993620301304

Purpose: To report a case of a patient with subretinal fluid (SRF) associated with choroidal nevus (CN), who was treated with selective retina therapy (SRT) and ultimately achieved resolution of the SRF. Observations: A 41-year-old man with SRF associated with CN in his right eye (RE) underwent ophthalmologic evaluation, including optic coherence tomography, fluorescein angiography (FA) and indocyanine green angiography. The best corrected visual acuity (BCVA) converted to the logarithm of the minimum angle of resolution (logMAR) was 0.00 in the RE. SRT (532 nm, 1.7 μs pulse duration, 30 pulses in 100Hz; Medical Laser Center Lübeck) was performed with the laser spots equally distributed across the FA leakage area. Until 20 months SRT was repeated several times because the SRF decreased every time in response to SRT, but was not completely resolved and sometimes increased with time. After performing 6 times of SRT session, leakage on FA stopped at 21 months follow-up and SRF was resolved at 31 months. At 60 months after the first SRT, there were no signs of malignant transformation, no SRF, and the BCVA in the RE was 0.22. Conclusions and Importance: SRT seems to be a useful treatment and proper clinical studies are necessary to establish the best treatment protocol for SRF associated with CN.