The combination of dantrolene and nimodipine effectively reduces 5-HT-induced vasospasms in diabetic rats

The combination of dantrolene and nimodipine effectively reduces 5-HT-induced vasospasms in diabetic rats

Abstract Diabetics have a higher risk of developing cerebral vasospasms (CVSP) after subarachnoid hemorrhagic stroke than non-diabetics. Serotonin (5-HT) is one of the key vasoconstrictors released in the hemorrhagic blood and an important contributor to the etiology of CVSP. The combination of the...

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Bibliographic Details
Main Authors: Marie Román, Laura García, Myrna Morales, María J. Crespo
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89338-6

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