Adipose‐specific ATGL ablation reduces burn injury‐induced metabolic derangements in mice

Adipose‐specific ATGL ablation reduces burn injury‐induced metabolic derangements in mice

Abstract Hypermetabolism following severe burn injuries is associated with adipocyte dysfunction, elevated beige adipocyte formation, and increased energy expenditure. The resulting catabolism of adipose leads to detrimental sequelae such as fatty liver, increased risk of infections, sepsis, and eve...

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Bibliographic Details
Main Authors: Supreet Kaur, Christopher Auger, Dalia Barayan, Priyal Shah, Anna Matveev, Carly M. Knuth, Thurl E. Harris, Marc G. Jeschke
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Clinical and Translational Medicine
Subjects:
adipose triglyceride lipase
browning
burns
FGF21
mitochondria
trauma
Online Access:https://doi.org/10.1002/ctm2.417

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