Pathomechanisms and Clinical Implications of Myasthenic Syndromes Exacerbated and Induced by Medical Treatments

Pathomechanisms and Clinical Implications of Myasthenic Syndromes Exacerbated and Induced by Medical Treatments

Myasthenic syndromes are typically characterized by muscle weakness and increased fatigability due to an impaired transmission at the neuromuscular junction (NMJ). Most cases are caused by acquired autoimmune conditions such as myasthenia gravis (MG), typically with antibodies against the acetylchol...

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Bibliographic Details
Main Authors: Martin Krenn, Anna Grisold, Philipp Wohlfarth, Jakob Rath, Hakan Cetin, Inga Koneczny, Fritz Zimprich
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
drug-related myasthenia
neuromuscular transmission
neuromuscular junction
drug-induced myasthenia
immune checkpoint inhibitors
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.00156/full

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