Sfrp1 protects against acute myocardial ischemia (AMI) injury in aged mice by inhibiting the Wnt/β-catenin signaling pathway

Sfrp1 protects against acute myocardial ischemia (AMI) injury in aged mice by inhibiting the Wnt/β-catenin signaling pathway

Abstract Background Aged patients suffering from acute myocardial ischemia (AMI) exhibit an increased mortality rate and worse prognosis, and a more effective treatment is currently in need. In the present study, we investigated potent targets related to Wnt/β-catenin pathway deregulation for AMI in...

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Bibliographic Details
Main Authors: Jing Tao, Xian Wei, Ying Huang, Fen Liu, Yun Wu, Dilare Adi, Yang Xiang, You Chen, Yi-tong Ma, Bang-dang Chen
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Soluble frizzled related protein 1 (Sfrp1)
Acute myocardial ischemia injury
Wnt/β-catenin pathway
Myocardial fibrosis
Aging
Online Access:https://doi.org/10.1186/s13019-020-01389-4

Internet

https://doi.org/10.1186/s13019-020-01389-4

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