EXPERIENCE OF ABATACEPT TREATMENT IN A PATIENT WITH ANTIBODY-POSITIVE IDIOPATHIC JUVENILE ARTHRITIS

EXPERIENCE OF ABATACEPT TREATMENT IN A PATIENT WITH ANTIBODY-POSITIVE IDIOPATHIC JUVENILE ARTHRITIS

The article represents a clinical case of severe Methotrexate- and Cyclosporine-resistant antibody-positive idiopathic juvenile arthritis in a teenage-girl. Treatment with T-cells costimulation inhibitor Abatacept was performed. In 24 weeks after treatment start inactive stage of disease was establi...

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Main Authors: T. M. Bzarova, E. I. Alekseeva, A. N. Fetisova, O. A. Klotchkova
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2012-03-01
Series:Voprosy Sovremennoj Pediatrii
Subjects:
children
juvenile idiopathic arthritis
abatacept
treatment
Online Access:https://vsp.spr-journal.ru/jour/article/view/137
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spelling doaj-49b721f881c548089eca2568ad58cd292021-07-28T21:15:29Zeng"Paediatrician" Publishers LLC Voprosy Sovremennoj Pediatrii1682-55271682-55352012-03-0111215516110.15690/vsp.v11i2.230137EXPERIENCE OF ABATACEPT TREATMENT IN A PATIENT WITH ANTIBODY-POSITIVE IDIOPATHIC JUVENILE ARTHRITIST. M. Bzarova0E. I. Alekseeva1A. N. Fetisova2O. A. Klotchkova3Scientific Centre of Children Health RAMS, MoscowScientific Centre of Children Health RAMS, Moscow; I.M. Sechenov First Moscow State Medical UniversityScientific Centre of Children Health RAMS, MoscowScientific Centre of Children Health RAMS, MoscowThe article represents a clinical case of severe Methotrexate- and Cyclosporine-resistant antibody-positive idiopathic juvenile arthritis in a teenage-girl. Treatment with T-cells costimulation inhibitor Abatacept was performed. In 24 weeks after treatment start inactive stage of disease was established: rheumatoid factor and cyclic citrullinated peptide antibodies serum concentrations were significantly lower, range of motion in the involved joints was completely restored, life quality increased to the level of the same age healthy adolescents.https://vsp.spr-journal.ru/jour/article/view/137childrenjuvenile idiopathic arthritisabatacepttreatment
collection DOAJ
language English
format Article
sources DOAJ
author T. M. Bzarova
E. I. Alekseeva
A. N. Fetisova
O. A. Klotchkova
spellingShingle T. M. Bzarova
E. I. Alekseeva
A. N. Fetisova
O. A. Klotchkova
EXPERIENCE OF ABATACEPT TREATMENT IN A PATIENT WITH ANTIBODY-POSITIVE IDIOPATHIC JUVENILE ARTHRITIS
Voprosy Sovremennoj Pediatrii
children
juvenile idiopathic arthritis
abatacept
treatment
author_facet T. M. Bzarova
E. I. Alekseeva
A. N. Fetisova
O. A. Klotchkova
author_sort T. M. Bzarova
title EXPERIENCE OF ABATACEPT TREATMENT IN A PATIENT WITH ANTIBODY-POSITIVE IDIOPATHIC JUVENILE ARTHRITIS
title_short EXPERIENCE OF ABATACEPT TREATMENT IN A PATIENT WITH ANTIBODY-POSITIVE IDIOPATHIC JUVENILE ARTHRITIS
title_full EXPERIENCE OF ABATACEPT TREATMENT IN A PATIENT WITH ANTIBODY-POSITIVE IDIOPATHIC JUVENILE ARTHRITIS
title_fullStr EXPERIENCE OF ABATACEPT TREATMENT IN A PATIENT WITH ANTIBODY-POSITIVE IDIOPATHIC JUVENILE ARTHRITIS
title_full_unstemmed EXPERIENCE OF ABATACEPT TREATMENT IN A PATIENT WITH ANTIBODY-POSITIVE IDIOPATHIC JUVENILE ARTHRITIS
title_sort experience of abatacept treatment in a patient with antibody-positive idiopathic juvenile arthritis
publisher "Paediatrician" Publishers LLC
series Voprosy Sovremennoj Pediatrii
issn 1682-5527
1682-5535
publishDate 2012-03-01
description The article represents a clinical case of severe Methotrexate- and Cyclosporine-resistant antibody-positive idiopathic juvenile arthritis in a teenage-girl. Treatment with T-cells costimulation inhibitor Abatacept was performed. In 24 weeks after treatment start inactive stage of disease was established: rheumatoid factor and cyclic citrullinated peptide antibodies serum concentrations were significantly lower, range of motion in the involved joints was completely restored, life quality increased to the level of the same age healthy adolescents.
topic children
juvenile idiopathic arthritis
abatacept
treatment
url https://vsp.spr-journal.ru/jour/article/view/137
work_keys_str_mv AT tmbzarova experienceofabatacepttreatmentinapatientwithantibodypositiveidiopathicjuvenilearthritis
AT eialekseeva experienceofabatacepttreatmentinapatientwithantibodypositiveidiopathicjuvenilearthritis
AT anfetisova experienceofabatacepttreatmentinapatientwithantibodypositiveidiopathicjuvenilearthritis
AT oaklotchkova experienceofabatacepttreatmentinapatientwithantibodypositiveidiopathicjuvenilearthritis
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